NCT06009289尚未招募4 期
Application of Precision Medicine to Phototherapy: a Stepped Care Approach to Consolidate Sleep and Slow Cognitive Decline in Older Adults
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Sleep fragmentation
研究概览
简要总结
This trial will examine scheduled exposure to bright light in the morning and afternoon as a countermeasure to sleep fragmentation in older individuals with mild cognitive impairment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 99 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Mild Cognitive Impairment
排除标准
- •Severe depression
- •Unstable psychiatric or medical disease
- •Acute infection
研究组 & 干预措施
Standard of care
Active Comparator
One hour of daily bright light exposure beginning one hour after wake time.
干预措施: Light therapy (Behavioral)
Stepped care
Experimental
One hour of daily bright light exposure in the afternoon
干预措施: Light therapy (Behavioral)
结局指标
主要结局
Sleep fragmentation
时间窗: 4 weeks
24 hour sleep wake patterns will be quantitated with a non-parametric measure, intradaily variation
次要结局
- Cognition(6 months)
- Mood(6 months)
研究者
Jamie M. Zeitzer, Ph.D.
Professor
Stanford University
研究点 (1)
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