The role of the left and right frontal hemisphere on mood and behaviour: A transcranial alternating current stimulation study

Completed

Conditions: fundamenteel onderzoek bij gezonde vrijwilligers
not applicable

Registration Number: NL-OMON41429

Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 44

Inclusion Criteria

18-35 Years of age, non smoking, right-handed, left dominant frontal brain activity in the beta band (20 Hz)

Exclusion Criteria

Skin disease, metal in cranium, use of psychotropic drugs, including cannabis, XTC, amphetamines and cocaine, epilepsy or family history of epilepsy, history of closed-head injury, history of neurological or psychiatric disorders, medication use (i.e., benzodiazepines, antidepressants and neuroleptica), cardiac pacemaker, electronic hearing devices, pregnancy.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Beta (13-30 Hz) oscillations as being assessed by four minute background EEG<br /><br>recorded from 32 scalp locations according to the International 10-20 EEG<br /><br>System using Ag-AgCl-tipped electrodes.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Cerebral physiology: Motor evoked potentials to single and paired-pulse<br /><br>transcranial magnetic stimulation (TMS) will be used to examine brain asymmetry<br /><br>by measuring intracortical inhibition/facilitation of the left and right<br /><br>hemisphere and interhemispheric connectivity;<br /><br><br /><br>Behavior and mood: Selective attention for emotional faces using the validated<br /><br>emotional Stroop task and mood using the 20-item Profile of Mood States (POMS)<br /><br>questionnaire.</p><br>