Hemisphere-specific activations of the ventral and dorsal premotor cortex during writing.

Completed

• Conditions: Gezonde populatie; Healthy population

• Registration Number: NL-OMON36851
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 16

Inclusion Criteria

Healthy right-handed persons aged 18-65 years.

Exclusion Criteria

Subjects who suffer from specific neurological or psychiatric disorders will be excluded. Subject who cannot go in the MRI scanner are also excluded. Also, subjects who are right-handed, but draw with their left hand are excluded.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Localization of condition-related increase of cerebral activations in the<br /><br>ventral and dorsal premotor cortex. This is caused by the detection of<br /><br>differences in (hemodynamic) BOLD responses, based on a comparison in subjects<br /><br>(left-right) and between the different experimental conditions.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Size of handwriting in millimeters will be measured. With EMG proximal and<br /><br>distal movements will be quantified during writing and drawing. The amount of<br /><br>white matter connections between Broca's area and the ventral premotor cortex<br /><br>will be quantified using probabilistic tractography in FSL.</p><br>