Transversus Abdominis Plane (TAP) Block for Laparoscopic Appendicectomy in Children: Opioid Saving and Alternative in the Curarization
Overview
- Phase
- N/A
- Intervention
- Curare
- Conditions
- Laparoscopic Appendectomy
- Sponsor
- University Hospital, Montpellier
- Enrollment
- 240
- Locations
- 1
- Primary Endpoint
- Painkiller of help consumption
- Last Updated
- 10 years ago
Overview
Brief Summary
The transversus abdominis plane (TAP) block is a regional anesthetic technique for post operative pain control after abdominal surgical procedures. Its effectiveness in children undergoing laparoscopic appendectomy has not been demonstrated. The investigators evaluate its analgesic efficacy over the first 24 post operative hours.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient hospitalized in surgery and infantile anesthesia unit or admitted in emergencies for an laparoscopic appendectomy surgery.
- •Patient whose general state corresponds to the classification of the American Society of Anesthesiologists (ASA) I to II
- •Patient member in a national insurance scheme
Exclusion Criteria
- •Patient with drilled appendicitis or peritonitis
- •Patient with a contraindication to local anesthesics
- •Patient with a contraindication to TAP block
- •Patient with allergies or known hypersensitivity to curare
Arms & Interventions
Group 1
Curare: Atracurium injection at 0.5 mg/kg
Intervention: Curare
Group 2
TAP block and curare: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg then atracurium injection at 0.5 mg/kg
Intervention: TAP block with Ropivacaine
Group 2
TAP block and curare: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg then atracurium injection at 0.5 mg/kg
Intervention: Curare
Group 3
TAP block: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg
Intervention: TAP block with Ropivacaine
Outcomes
Primary Outcomes
Painkiller of help consumption
Time Frame: up to 24 hours after surgery
Quantity of analgesic of help (Nalbuphine, Nubain®, Dupont Pharma, Paris, France) taken after the surgery.
Secondary Outcomes
- Pain intensity after surgery(up to 24 hours)
- First demand of analgesic of help(up to 12 hours)