DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve
- Registration Number
- NCT06572215
- Lead Sponsor
- King's College Hospital NHS Trust
- Brief Summary
This is a feasibility study to assess new, more practical ways of measuring renal reserve.
- Detailed Description
Quantification of glomerular filtration rate (GFR) over time is the standard assessment of kidney function. In clinical practice, the endogenous marker, 'serum creatinine' concentration, is used as a static assessment of kidney function to estimate GFR. However, serum creatinine fails to increase until at least 50% of kidney tissue is lost,\[2\] thus is an i...
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Not provided
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Exclusion Criteria
Not provided
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with hyperfiltration Dapagliflozin - Healthy Participants Dapagliflozin -
- Primary Outcome Measures
Name Time Method Change in eGFR from baseline to 2hours after oral protein load 2 hours
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
King's College Hospital
🇬🇧London, United Kingdom