DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve
Recruiting
- Conditions
- Chronic Kidney Diseases
- Registration Number
- NCT06572215
- Lead Sponsor
- King's College Hospital NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Inclusion:<br><br>Patients with sickle cell nephropathy, diagnosed clinically or histologically. Sickle<br>Cell patients will be confirmed Hb SS and eGFR (CKD-EPI) = 135 ml/min/1.73m2 OR Previous<br>living kidney donation Age = 4No contraindication or known allergy to any trial<br>medications. Willing and able to provide written informed consent<br><br>Exclusion:<br><br>Aged < 40 Unable or unwilling to provide informed consent Breastfeeding or pregnant women<br>Patients involved in other interventional research studies.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in eGFR from baseline to 2hours after oral protein load
- Secondary Outcome Measures
Name Time Method