跳至主要内容
临床试验/CTRI/2024/10/074694
CTRI/2024/10/074694尚未招募2/3 期

A controlled clinical study to evaluate the efficiency of Ingudi taila over Jatyadi taila in management of Dushta vrana (Chronic wound)

Dr Anusha K1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2027年9月20日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Assessment of Objective parameter-

研究概览

简要总结

A wound is a break in the integrity of the skin or tissue often, which may be associated with disruption of the structure and function . Wounds can be classified as Acute and Chronic wounds. Chronic wounds are defined as wounds that have failed to proceed through the orderly process that produces satisfactory anatomic and functional integrity.

Proper wound healing is required to re-establish disturbed anatomic continuity and functional status of the skin. Inappropriate and inadequate treatment of Acute wound is the commonest cause of chronic wound. So if the wound is not managed properly, it may result in a local and systemic infection that leads to septicemia. Later the tissue necrosis leads to gangrene which necessitates further amputation . Treatment of wound was probably the most common medical problem faced by human beings. The frequency of injuries was more common than any other disease. The prevalence rate of chronic wound in the community was reported as 4.5% per 1000 population. Few common management of wound are Debridement, cleaning wound and dressing. De-sloughing is done by mechanically or chemically.

According to estimation from the World Health Organization, 80% of the world’s population relies on traditional medicines for their primary healthcare.

In Ayurvedic context, wound can be correlated to vrana and Chronic wound to Dushta vrana on the basis of Dushta vrana lakshana expained by Acharya Sushruta.

The word Vrana denotes Vrana Gatra Vichurnane which means the tissue disruption.

Healing of wounds is one of the important areas of clinical medicine described in many Ayurvedic texts under the heading Vrana ropana. Although vrana shodhaka and ropanaka drugs are described in detail in Ayurvedic Samhitas, a systematic treatment of these concepts may be found in Sushruta Samhita under the heading of Shashti upakrama, of which taila upakrama is one among them. Various drugs has been mentioned for Dushta vrana, out of them Ingudi is specifically selected for its Tikta, kashaya rasa, Kapha Vatahara action, and for treatment of chronicity of wound due to its specific property i.e., Krimigna prabhava.

Acharya Sushruta has mentioned Ingudi taila for Dushta vrana  which is inexpensive, easily available and minimal drugs used. On the other hand Jatyadi taila which is commonly used for Dushta vrana and its efficacy has proven to be effective. Hence an attempt is made to evaluate the efficacy of Ingudi taila with Jatyadi taila in management of Dushta vrana (Chronic wound).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patient of age Group between 18-60 years, either of gender and having clinical features of Dushta vrana like Vedanayukta [Pain], Deergakalanubandi [chronic], Sravayukta [discharge] and dushta vrana having size less than 6x6cm [l x b] and 2cm depth.

排除标准

  • Patients with HIV Positive, HBsAg Positive, known case of Tuberculosis, Uncontrolled Diabetes Mellitus, Malignant ulcers and Burns.

结局指标

主要结局

Assessment of Objective parameter-

时间窗: 3 weeks

Pain,

时间窗: 3 weeks

Discharge

时间窗: 3 weeks

次要结局

  • Assessment of-(Size,)

研究者

发起方
Dr Anusha K
申办方类型
Other [Self Sponsoring]
责任方
Principal Investigator
主要研究者

Dr Anusha K

Shree Jagadguru Gavisiddeshwara Ayurvedic Medical College and Hospital, Koppal

研究点 (1)

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