A Randomized Clinical Trial to Compare the Efficacy of Vinegar Dressing Versus Normal Saline Dressing in the Treatment of Diabetic Foot Ulcers
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 84
- 主要终点
- Rate of Negative Cultures
研究概览
简要总结
This study is investigating the effectiveness of two different types of wound dressings in treating diabetic foot ulcers (DFUs), a common complication of diabetes that can be difficult to heal. The study will compare the use of vinegar dressings to normal saline (saltwater) dressings to see which one helps heal the wound faster and more effectively.
People with diabetic foot ulcers often struggle with infections and slow healing. The goal of this study is to determine if vinegar, a simple and affordable treatment, works better than saline in improving wound healing and reducing infections. The study will measure how quickly the wound heals, how much dead tissue is removed, and whether the bacteria in the wound disappear.
This study will involve patients with infected diabetic foot ulcers. Participants will be randomly assigned to receive either vinegar or saline dressing. The results will help determine the best and most cost-effective treatment for diabetic foot ulcers, potentially making it easier for patients to access better care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 20 to 65 years.
- •Gender: Both male and female participants are included.
- •Condition: Patients with Grade 3 and 4 infected diabetic foot ulcers (DFU) according to the Wagner classification.
排除标准
- •Wagner Grades 1, 2, 5, and 6 diabetic foot ulcers.
- •History of Radiotherapy.
- •History of Chemotherapy.
- •Use of Steroids.
- •Use of Immunosuppressive drugs.
- •Allergy to vinegar.
研究组 & 干预措施
Vinegar Dressing
干预措施: Vinegar Dressing (Other)
Normal Saline Dressing
干预措施: Normal Saline Dressing (Other)
结局指标
主要结局
Rate of Negative Cultures
时间窗: From enrollment to 8 weeks after treatment initiation
Definition: The proportion of participants whose wound cultures become negative (no bacterial growth) by the end of the treatment period (e.g., 3 weeks or 8 weeks). Measurement: The swab cultures will be taken weekly, and the presence or absence of bacterial infection will be recorded until the wound is culture-negative. Rationale: This outcome is crucial as it directly measures the effectiveness of vinegar dressing in reducing wound infection compared to normal saline dressing.
次要结局
未报告次要终点
研究者
Dr. MIAN MUHAMMAD BILAL
Principal Investigator
University of Health Sciences Lahore