Physiologic and Expectancy Effects of Stress-reducing Aroma in Older Adults
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 92
- 试验地点
- 2
- 主要终点
- Percent of Baseline Level of Salivary Cortisol
研究概览
简要总结
The study purpose is to evaluate efficacy of stress-reducing aromatherapy and learn about how aromatherapy works.
详细描述
The study purpose is to evaluate efficacy of stress-reducing aromatherapy and learn about how aromatherapy works by comparing participants' physiologic responses to laboratory challenge tasks with and without experiencing aromatherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •in good physical and cognitive health
- •reporting moderate level of stress
- •able to perceive aromas
- •able to understand and follow study instructions
排除标准
- •taking medications affecting central nervous system (CNS) function or physiologic measures (e.g. steroids or neuroleptics)
- •reporting smell sensitivities or allergies
- •smoking presently or in the past less than one year prior to enrollment
研究组 & 干预措施
stress reducing aroma
aroma with reported stress reducing effects
干预措施: aroma (Other)
Placebo aroma 1
干预措施: aroma (Other)
Placebo aroma 2
干预措施: aroma (Other)
结局指标
主要结局
Percent of Baseline Level of Salivary Cortisol
时间窗: assessed at baseline (60 min prior to aroma exposure and stress), stress battery (30 min after aroma exposure and during stress), post-stress (60 min after completing stress battery)
Percent of baseline level of salivary cortisol (values greater than baseline indicate increased stress)
次要结局
- Cognitive Performance: Percent Change From Baseline in Digit Span Backward Task Score(Baseline (60 min prior to aroma exposure and stress), post-stress (60 min after completing stress battery))
- Electroencephalography (EEG) Frontal Asymmetry(assessed at baseline (60 min prior to aroma exposure and stress), at the onset of aromatherapy exposure, stress battery (30 min after aroma exposure and during stress), post-stress (60 min after completing stress battery))
研究者
Barry S. Oken
Professor
Oregon Health and Science University