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Clinical Trials/NCT04809077
NCT04809077
Completed
Not Applicable

Focus on the Humeral Component Following Reverse Shoulder Arthroplasty: Radiographic and Clinical Findings

Universitaire Ziekenhuizen KU Leuven1 site in 1 country123 target enrollmentJune 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rotator Cuff Arthropathy
Sponsor
Universitaire Ziekenhuizen KU Leuven
Enrollment
123
Locations
1
Primary Endpoint
Shoulder X-ray
Status
Completed
Last Updated
last year

Overview

Brief Summary

Reverse total shoulder arthroplasty has been widely used in the treatment of rotator cuff arthropathy. Follow-up has historically focused on the glenoid component because of problems with fixation and scapular notching leading to functional failure. Since several patients have shown cortical thinning of the proximal lateral humeral cortex during follow-up, further research is recommended to evaluate the cause and clinical impact of these radiographic changes. The goal of this study is to collect long-term radiographic and clinical data in order to facilitate the identification of risk factors.

Detailed Description

Reverse total shoulder arthroplasty has been widely used in the treatment of rotator cuff arthropathy. Follow-up has historically focused on the glenoid component because of problems with fixation and scapular notching leading to functional failure. Fixation of the humeral component has evolved from cemented to mostly uncemented with diaphyseal of metaphyseal press-fit stems. Bony changes around the stem reflect the bone-implant interface; research to evaluate and interpret these changes is insufficient at this moment. Since several patients have shown cortical thinning of the proximal lateral humeral cortex during follow-up, further research is recommended to evaluate the cause and clinical impact of these radiographic changes. The goal of this study is to collect long-term radiographic and clinical data in order to facilitate the identification of risk factors.

Registry
clinicaltrials.gov
Start Date
June 1, 2021
End Date
April 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Minimum age of 18 years old
  • Total shoulder replacement using a reverse type implant (Delta Xtend or Zimmer TM) between 2007 and 2017 in UZ Leuven
  • Primary indication for surgery is rotator cuff arthropathy
  • Informed consent obtained

Exclusion Criteria

  • Total shoulder replacement in post septic arthritis.
  • Total shoulder replacement in post-instability arthritis.
  • Revision total shoulder arthroplasty.
  • Posttraumatic total shoulder arthroplasty (after failed index operation)

Outcomes

Primary Outcomes

Shoulder X-ray

Time Frame: up to 20 months

To describe bony reaction at the bone-implant interface for the humeral component of a reverse shoulder arthroplasty. End-point radiographs will be compared to radiographs taken postoperatively in order to define stress shielding and/or bone resorption in the 5 humeral zones described by Nagels et al.

Secondary Outcomes

  • Constant-Murley score(up to 20 months)
  • Anchor Question Shoulder Score(up to 20 months)
  • Net Promotor Score (NPS)(one time visit)
  • Clinical outcome(up to 20 months)
  • Short Form 36 Health Survey Questionnaire (SF-36)(up to 20 months)

Study Sites (1)

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