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Clinical Trials/NCT03610113
NCT03610113
Completed
Not Applicable

Reverse Shoulder Arthroplasty Versus Conservative Treatment For Complex Proximal Fractures in Elderly Patients

Consorci Sanitari de l'Anoia1 site in 1 country81 target enrollmentSeptember 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Humeral Fractures
Sponsor
Consorci Sanitari de l'Anoia
Enrollment
81
Locations
1
Primary Endpoint
Pain, Mobility, Strenght and Daily Life Activities. (Functional Outcome)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Reverse shoulder prosthesis has recently emerged as an acute treatment for complex proximal humeral fractures. Promising functional results have been reported in observational papers.

However, no clinical trials have yet been reported when comparing the conservative treatment to surgical treatment through the use of reverse shoulder arthroplasty.

Detailed Description

Introduction The proximal humeral fractures are frequent in the investigator's environment. Among them, about 20% are considered as complex features. Conservative treatment has traditionally offered an extensive range of results. The reverse shoulder prosthesis as a treatment for acute fractures of the proximal humeral in the elderly population has changed the therapeutic approach of this acute pathology. However, high-level evidence-based studies are still not available, when comparing the conservative treatment with the treatment with reverse shoulder prosthesis. Objective To compare the functional results and complications of elderly patients presenting acute complex fractures of the proximal humerus through two types of treatments; conservative treatment and treatment with reverse shoulder prosthesis. Methodology A prospective, multicentre and randomized study comparing conservative treatment with the surgical treatment at two years followup by the use of functional shoulder assessment (Constant scale), complications and re-interventions associated with each treatment. The quality of life will also be analyzed through the SF-36 health questionnaire Expected results The null hypothesis of the work is based on the appearance of non-significant differences between the two groups of the study (conservative vs. surgical treatment), concerning functional status, complications, and re-interventions

Registry
clinicaltrials.gov
Start Date
September 2016
End Date
August 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Consorci Sanitari de l'Anoia
Responsible Party
Principal Investigator
Principal Investigator

Joan Miquel

Orthopaedic Surgeon, Principal Investigator

Consorci Sanitari de l'Anoia

Eligibility Criteria

Inclusion Criteria

  • Patients with mental conditions available for rehabilitation protocols
  • Patients presenting a 3 or 4 part proximal humeral fracture

Exclusion Criteria

  • Extremely displaced fractures with no bony contact or less than 1 cm.
  • Cognitive impairment (Pfeiffer test \>3)
  • Shoulder dislocations
  • Unable to sign informed consent or unable to respond to questionnaires
  • Trauma or previous surgery of the extremity
  • Open or pathological fracture
  • Vascular or neurological injury associated
  • Unable to collaborate with rehabilitation
  • Patients with serious comorbidities that discourage surgery

Outcomes

Primary Outcomes

Pain, Mobility, Strenght and Daily Life Activities. (Functional Outcome)

Time Frame: 1 year

Constant-Murley Score. The Constant-Murley score (CMS) is a 100-points scale composed of a number of individual parameters. These parameters define the level of pain and the ability to carry out the normal daily activities of the patient.The Constant-Murley score was introduced to determine the functionality after the treatment of a shoulder injury and it ranges from 0 to 100 points. The test is divided into four subscales: pain (0 to 15 points), activities of daily living (0 to 20 points), strength (0 to 25 points) and range of motion: forward elevation (0 to 10 points), external rotation (o to 10 points), abduction (0 to 10 points) and internal rotation of the shoulder (0 to 10 points). Then, those range of motion items allocate from 0 to 40 points to the global score. The higher the score, the higher the quality of the function.

Secondary Outcomes

  • Number of participants with treatment-related surgical reinterventions(1 year)
  • Number of participants with treatment-related shoulder joint infection(1 year)
  • Number of participants with treatment-related Implant dislocation(1 year)

Study Sites (1)

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