Contrast Enhanced Ultrasonography (CEUS) of Patients With Crohn's Disease
Terminated
- Conditions
- Crohn's Disease
- Registration Number
- NCT01074580
- Lead Sponsor
- Haukeland University Hospital
- Brief Summary
The purpose of this study is investigate if high frequency sonography and contrast enhanced sonography can be used to predict remission in patients with deterioration of Crohn's disease treated with steroids or tumor necrosis factor (TNF) alfa inhibitors.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Deterioration of Crohn's disease
- CDAI>150
- Treated with systemic steroids or TNF alfa inhibitors
- Lesion found on ultrasound
Exclusion Criteria
- Disease location not reachable with ileocolonoscopy
- Pregnancy
- Acute coronary disease
- Unstable coronary disease
- Previous allergic reaction to SonoVue or its components
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Remission defined by Crohns disease activity index (CDAI)<150 52 weeks from inclusion
- Secondary Outcome Measures
Name Time Method Mucosal healing on ileocolonoscopy. Defined by Simple Endoscopic Index for Crohn's disease (SES-CD) 12 weeks Surgical treatment for Crohn's disease during follow up. (Surgery for perianal disease not included.) 52 weeks
Trial Locations
- Locations (1)
Department of Medicine, Haukeland University Hospital
🇳🇴Bergen, Hordaland, Norway