Tranexamic acid in displaced femoral neck fracture treated with bipolar hemiarthroplasty: a randomized, controlled trial of topical versus intravenous administration.

Phase 3

• Conditions: Hip fracture; Closed fracture neck of femurBipolar hemiarthroplastyHip fractureTopical tranexamic acidintravenous tranexamic acidfracture neck of femurblood lossthromboembolic complications; Closed fracture neck of femur; Bipolar hemiarthroplasty; Topical tranexamic acid; intravenous tranexamic acid; fracture neck of femur; blood loss; thromboembolic complications

• Registration Number: TCTR20210316006
• Lead Sponsor: Ratchasapisek Sompoch

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-16
• Study Completion: 2023-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

1. Diagnosis fracture neck of femur
2. Age more than 60 years old
3. Household ambulatory
4. Low energy mechanism
5. Complete inform consent.

Exclusion Criteria

-1.Allergy to TXA
2.Prior history of thromboembolic disease
3.Prior history of stroke
4.Prior history of ischemic heart disease
5.Prior history of seizure
6.Congenital or acquired coagulopathy
7.Renal or liver dysfunction

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood loss calculated total blood loss by Gross formula calculated total blood loss by Gross formula

Secondary Outcome Measures

Name	Time	Method
Blood transfusion 72 hours Packed red cell after surgery,Complications 6 months Clinical symptoms