effect of aripiperazole in treatment of psychotic mania
Not Applicable
- Conditions
- Condition 1: mania. Condition 2: bipolar disorder.bipolar affective disorder
- Registration Number
- IRCT201409176691N2
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
criteria: Age more than 18 years; Diagnosis of Bipolar disorder with psychotic symptom based on DSM-IV TR; Ongoing treatment with Litium as a mood stabilazor with seromic level between 0.8-1.2meq/L ; patient with YMRA>20.Exclusion criteria: Mental Retardation; Pregnancy or Breast Inclusion feeding;Any chronic medical problem; substance abuse; Any other psychiatric Disorder in Axis I OR II;Allergic to Aripiprazole and other Atypical Antipsychotic drug ;History of epileptic disorder; Delirium state.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of manic phase and psychotic symptom. Timepoint: Baseline and days 7-14-21 after beginig of treatment. Method of measurement: YMRS.
- Secondary Outcome Measures
Name Time Method Akatezia. Timepoint: days 2-4-7-10 after beginig of treatment then every weeks. Method of measurement: BARS.;Extrapyramidal. Timepoint: days 2-4-7-10 after beginig of treatment then every weeks. Method of measurement: AIMS.;Diskinesia. Timepoint: days 2-4-7-10 after beginig of treatment then every weeks. Method of measurement: SAS.