Effect of Daily Consumption of Moringa Oleifera Leaves on Glycemic Control of Saharawi Women With Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Fasting glucose
研究概览
简要总结
The objective of this clinical trial was to understand whether supplementation of Moringa oleifera leaf powder improved glycemic management in Sahrawi women with type 2 diabetes living in refugee camps. The main question sought to be answered was:
- Does daily supplementation of Moringa oleifera leaf powder, in addition to oral hypoglycemic therapy, improve glycosylated hemoglobin and fasting blood glucose?
Researchers compared Moringa supplementation with no Moringa consumption to see if Moringa oleifera worked to improve glycemic control.
Participants had to:
- Take Moringa oleifera leaves daily or abstain from consuming Moringa for 3 months.
- Consistently take prescribed oral hypoglycemic agents
- Undergo clinical examinations and measurement of biochemical, metabolic and body composition parameters at the time of recruitment and at the end of the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of type 2 diabetes for at least 1 year
- •Absence of advanced retinopathy, terminal renal failure, active diabetic ulcers, amputations, and heart failure
- •Treatment with only oral hypoglycemic drugs.
排除标准
- •Diagnosis of type 1 diabetes
- •Pregnancy or lactation
- •Treatment with insulin.
研究组 & 干预措施
Moringa
The experimental group received for 3 months a daily supplementation of 10g of Moringa oleifera leaf powder to consume within the two main meals.
干预措施: Supplementation of Moringa oleifera leaf powder (Dietary Supplement)
Control
The control group were asked to refrain from consuming Moringa oleifera leaves throughout the study period (3 months).
结局指标
主要结局
Fasting glucose
时间窗: Fasting glucose was measured at recruitment and at the end of the study (three months)
Glycosylated hemoglobin (HbA1c)
时间窗: Glycosylated hemoglobin was measured at recruitment and at the end of the study (three months)
次要结局
- Hip circumference(Hip circumference were measured at recruitment and at the end of the study (3 months))
- BMI(BMI were measured at recruitment and at the end of the study (3 months))
- Waist circumference(Waist circumference were measured at recruitment and at the end of the study (3 months))
- % body fat(% of body fat were measured at recruitment and at the end of the study (3 months))
- Blood pressure(Systolic and diastolic blood pressure were measured at recruitment and at the end of the study (3 months))
研究者
Alberto Battezzati
Professor
University of Milan