Effect of Noradrenaline Infusuion Versus Phenyephrine Infusion in Improving Tissue Perfusion in HIPEC
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- SERUM LACTATE IN ABG
研究概览
简要总结
ABG PARAMETERS ARE CHANGED DURING HIPEC, WE TRIED TO FIND COMPARISON BETWEEN NORADRENALINE AND PHENYLEPHRINE IN OPTIMIZING ABG PARAMETERS THAT REFLECTS ORGAN PERFUSIONS ESPECIALLY SERUM LACTATE
详细描述
Arterial blood gas testing is considered one of the most important and widely used test in the detection of acidosis, alkalosis, electrolytes disturbance and tissue perfusion. in regard to tissue perfusion serum lactate above 4 mmol/L indicates poor tissue perfusion. serum lactate could be measured at ABG or separately. in this study we will test the effect of both noradrenaline and phenylephrine on lactate level at ABG during the stage of HIPAC in managing abdominal cancer patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 35 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CANCER PATIENTS ENROLLED FOR HIPEC
排除标准
- •DRUG SENSITIVITY
研究组 & 干预措施
NORADRENALIN
NORADRENALINE INFUSION
干预措施: NORADRENALIN (Drug)
PHENYLEPHRINE
PHENYLEPHRINE INFUSION
干预措施: PHENYLEPHRINE (Drug)
结局指标
主要结局
SERUM LACTATE IN ABG
时间窗: IMMEDIATELY POSTOPERATIVELY
LANDMARK FOR TISSUE AND ORGAN PERFUSION
次要结局
未报告次要终点
研究者
Abdelrhman Alshawadfy
Clinical professor
Suez Canal University