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临床试验/CTRI/2025/03/082944
CTRI/2025/03/082944尚未招募不适用

A Randomized Control Study Of Mean Arterial Pressure Monitoring In Paediatric Septic Shock On Vasoactive Therapy

Datta Meghe Institute of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2025年3月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
46
试验地点
1
主要终点
mean arterial pressure with better survival and less PICU stay

研究概览

简要总结

After obtaining the informed consent from the parents and guardians , children will included in the study , allCritically ill children between the age of 1 month  to 18 years with septic shock on vasoactive drugs admitted in PICU , avbrh , Sawanagi,Meghe , wardha , will be included the design of this study is randomized was performed with the use of computer generated assignment sequence, the blood pressure is assessed and measured according to age , height , sex of the child , the patients are divided into two groups , high targeted bp and low targeted group , in the low targeted group the bp is maintained between the. 40 th -50tg centile and in high targeted blood pressure is maintained at 50 th - 60 th centile range with titration of fluids and vasoactive drugs and the analysis can be done based on variables for quantitative variables will be expressed as standard deviation , and use t tests to compare each group and for qualitative variable chisquare test is used , and the main objective to determine the outcome of shock with low and high targeted MAP and to study end organ damages in cases of septic shock

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
1.00 Month(s) 至 18.00 Year(s)(—)
性别
All

入选标准

  • 1.Critically ill children between the age of 1 month to 18 years admitted to PICU.
  • 2.Patients with septic shock on vasoactive drugs.

排除标准

  • 1.Refusal of consent.
  • 2.Patient with hypertension.

结局指标

主要结局

mean arterial pressure with better survival and less PICU stay

时间窗: 3 days

次要结局

  • Duration of mechanical ventilation(Duration of hospital stay)

研究者

发起方
Datta Meghe Institute of Higher Education and Research
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

battula gayatri

Datta Meghe Institute of Higher Education and Research,

研究点 (1)

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