ISRCTN50312145
Completed
未知
A multicentre Prospective Randomised Controlled Trial of Thrombosis Prophylaxis with Warfarin in Cancer Patients with Central Venous Catheters (CVCs)
ConditionsCancer
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Cancer
- Sponsor
- Cancer Research UK (UK)
- Enrollment
- 1400
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19217991
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Histologically or clinically confirmed diagnosis of cancer
- •2\. Patients who are due to have a CVC inserted for administration of chemotherapy
- •3\. Aged at least 16
- •4\. Adequate haematological, hepatic and renal function
- •5\. Able to provide written informed consent
Exclusion Criteria
- •1\. Patients with contraindication to warfarin (including congenital bleeding disorders, anatomic lesions that bleed e.g. duodenal ulcers and profound concomitant therapy interaction)
- •2\. Patients currently on warfarin
- •3\. Patients who have previously been entered into WARP
- •4\. Use of CVC for additional purposes with the exception of antibiotic therapy and blood products
- •5\. Pregnant or lactating women
- •6\. Fertile persons, not taking adequate contraceptive measures
Outcomes
Primary Outcomes
Not specified
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