Correlation Between Refraction and Biometric Parameters

• Conditions: Refractive Errors

• Registration Number: NCT04346251
• Lead Sponsor: Sun Yat-sen University

Brief Summary

To document the refractive status of Chinese schoolchildren and evaluate the association between the degree of refraction and biometric parameters.

Detailed Description

In this study, we will analyze the refractive status of schoolchildren and compare the ocular biometrics, including spherical equivalent refraction (SER), pupil distance (PD), corneal curvature (CC), high order aberration (HOA), and central corneal thickness (CCT) between boys and girls. Additionally, we investigate the correlation between the SER in diopters and the other biometric parameters, including PD, CC, HOA, CCT, and body mass index (BMI).

Study Timeline

• Study Start: 2017-11-01
• Primary Completion: 2019-11-30
• Status Verified: 2020-04
• Study First Submitted: 2020-04-10
• Study First Submitted QC: 2020-04-10
• Last Update Submitted: 2020-04-10
• Study First Posted: 2020-04-15
• Last Update Posted: 2020-04-15
• Study Completion: 2020-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Schoolchildren aged from 6 to 15 years

Exclusion Criteria

• with previous histories of cataracts, keratitis, strabismus, or other visual impairments
• with history of previous eye surgery
• with unreliable auto-refraction values
• unwilling to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
refractive error in diopters and biometric Parameters	up to 1 year	Multiple regression analysis will be performed to evaluate the correlations between SER and the other biometric parameters

Trial Locations

Locations (1)

Zhognshan Ophthalmic Center, Sun Yat-sen University; 🇨🇳 Guangzhou, Guangdong, China