Comparison of Anaesthetic Effectiveness of Different Volumes of Articaine for Inferior Alveolar Nerve Block in Molar Teeth with Symptomatic Irreversible Pulpitis
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 78
- 试验地点
- 4
- 主要终点
- Pain Control
研究概览
简要总结
This is a randomized controlled trial comparing the anaesthetic efficacy of 1.8 and 3.6 mL of Articaine for inferior alveolar nerve block when treating mandibular molars with Irreversible Pulpitis
详细描述
An informed written consent of the patients will be obtained. (Annex-A).
Demographic details (including name, age, gender, contact) will be obtained on data collection forms. (Annex-B).
The principal investigator will perform the local anesthetic injection and the participants will be assigned to one of the groups.
Group 1: 1.8 mL articaine Group 2: 3.6 mL articaine
Before starting the treatment i.e. before administration of the anesthetic solution, each participant will receive an explanation regarding the Heft-Parker visual analog pain scale (VAS) and asked to rate their pain on a self-report questionnaire.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy patients, including age group 18-55 years old
- •Mandibular first molar tooth with symptomatic irreversible pulpitis
- •Normal periapical radiographic appearance
- •Moderate pain on Heft-Parker VAS ( > 54 mm and < 114 mm )
- •Lingering pain or prolonged response to the cold testing (more than 10 seconds)
- •Positive response to electric pulp testing
排除标准
- •Patients who have taken analgesic or anti-inflammatory drugs within 6 hours before treatment visit
- •History of allergy to 4% articaine or epinephrine
- •Patients with systemic diseases
- •Pregnant or lactating patients
- •Teeth with severe periodontal disease
- •Teeth with periapical radiolucency
- •Any type of medication that could potentially interact with the anesthetic solution (antihypertensives)
结局指标
主要结局
Pain Control
时间窗: 30 to 45 minutes
Pain was recorded on a self-report questionnaire using the visual analog pain scale (VAS) VAS was used for gauging pain before the administration of the anesthetic solution, after the cold test was performed, and during the endodontic therapy. The VAS scores were designated as; 0= no pain 1-3= mild pain 4-7= moderate pain 8-10= severe pain
次要结局
未报告次要终点
研究者
Kanza Zafar
Dr. Kanza Zafar, Principal Investigator and Resident Operative Dentistry and Endodontics
Armed Forces Institute of Dentistry, Pakistan