Anesthetic Efficacy of 1.8 ml Compared to 3.6 ml of Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 主要终点
- Anesthetic success
研究概览
简要总结
The aim of the study is to compare the anesthetic efficacy and need for supplemental anesthesia of 1.8 ml compared to 3.6 ml of 4% articaine buccal infiltration in mandibular molars with symptomatic irreversible pulpitis.
详细描述
Patients with moderate-to-severe pain due to symptomatic irreversible pulpitis will be included. Patients will be randomly assigned into two groups to receive either 1.8 ml 4% articaine buccal infiltration or 3.6. ml 4% articaine buccal infiltration before single visit root canal treatments. Intraoperative pain will be assessed using an 11-point numerical rating scale (NRS) so that anesthetic success will be defined as no to mild intraoperative pain. The need for supplemental anesthesia will also be recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy patients who are categorized as I or II according to The American Society of Anesthesiologists (ASA class I or II).
- •No sex predilection
- •Patients with symptomatic irreversible pulpitis
- •Patient with the ability to understand and use pain scales.
- •Patients who accept to enroll in the study.
排除标准
- •Patients' allergies to any of the drugs or materials used in the study.
- •Pregnant and lactating females.
- •Patients taking analgesics in the last 6-8 hours.
- •Patients having more than one symptomatic tooth in the same quadrant
研究组 & 干预措施
1.8 ml 4% articaine buccal infiltration.
干预措施: 1.8 ml 4% Articaine hydrochloride (Drug)
3.6 ml 4% articaine buccal infiltration
干预措施: 3.6 ml 4% Articaine hydrochloride (Drug)
结局指标
主要结局
Anesthetic success
时间窗: During the procedure
Will be measured by 11-point numerical rating scale NRS. The success will be defined as no or mild pain (NRS 0 or less than 3) and the failure will be defined as moderate to severe pain (NRS more than 3).
次要结局
- Need for supplemental anesthesia(During the procedure)
研究者
Hebatullah Moheb Ibrahim
Principle investigator
Cairo University