Optimisation of DBS Therapy for Parkinson’s Disease Patients using Electrophysiological Biomarkers
Not yet recruiting
- Conditions
- G20.01G20.11
- Registration Number
- DRKS00026257
- Lead Sponsor
- niversitätsklinikum Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
• Patients with implanted PerceptTM PC Neurostimulator
• Patients with IPS
• Patients with bilaterally implanted lead electrodes in the STN
• Declaration of consent
• Patient age must be between 18 and 80 years
Exclusion Criteria
• Patients with severe cognitive or psychiatric deficits
• Patients that are non-cooperative or non-competent
• Patients with tremor dominant IPS
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences in ß-activity between patient’s motor off-state and on-state according to UPDRS-III
- Secondary Outcome Measures
Name Time Method ß-activity in dependence of medication intake