Target Planning for Placement of DBS-electrodes and Follow-up of the Clinical Efficacy of Stimulation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Movement Disorders
- Sponsor
- University of Zurich
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- neurological outcome
- Status
- Enrolling By Invitation
- Last Updated
- 2 years ago
Overview
Brief Summary
Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement.
The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires.
- Trial with surgical intervention
Detailed Description
Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement. The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
neurological outcome
Time Frame: 5 years
UPDRS