A comparative split face study on the efficacy of fractional co2 laser versus fractional co2 laser with topical insulin in the management of atrophic acne scars
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Improvement in ECCA global score
研究概览
简要总结
Acne is chronic inflammatory disorder of pilosebaceous units caused byvarious pathological mechanisms. The clinical features can vary from noninflammatory comedones, inflammatory papules, pustules and nodules at varyingdegrees of depth. Post inflammatory lesions will vary from post inflammatoryhyperpigmentation, atrophic and hypertrophic/keloidal scars. Atrophic scars areicepick ,rolling and boxcar type scars. Many modalities of treatment are available to treat atrophic acne scars.Chemical peeling , Fractional CO2 laser, PRP, Microneedling, MNRF (Microneedling Radiofrequency) are some of the treatment options available.
In my study I am goingto compare the efficacy of Fractional CO2 laser versus Fractional CO2 laserwith topical insulin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients of either sex above 18 years & below 45 years with atrophic acne scars 2.Patients willing to give a written informed consent.
排除标准
- •Before starting the study 1.Pregnant and lactating women.
- •2.Patients on anticoagulants/ immunosuppressive therapy 3.Patients with HIV, Bleeding and coagulation disorders, Diabetes mellitus and keloidal tendencies.
- •4.Patients with active local infection 5.Patients with active inflammatory acne 6.Patients on isotretinoin /taken within 6 months During Study 1.If patient wants alternate treatment during the study.
- •2.If patient wants to discontinue the treatment.
结局指标
主要结局
Improvement in ECCA global score
时间窗: 12 weeks after treatment
次要结局
- Patient satisfaction score(12 weeks after treatment)