A Pilot Study of Topical honey for the treatment ofCold Sores

Completed

• Conditions: Cold sores; Skin - Dermatological conditions

• Registration Number: ACTRN12612000564853
• Lead Sponsor: Medical Research Institute of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-05-25
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Aged 16 or over at the time of enrolment
At least two episodes of cold sores in the past 12 months

Exclusion Criteria

Known immune suppression or receiving medication likely to cause immune suppression
Requirement for systemic antiviral or antibiotic therapy, as judged by treating doctor
Known or suspected allergy to honey or acyclovir
Any other condition which, at the investigators discretion, it is believed may present a safety risk or impact the feasibility of the study or the study results

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Healing time (defined as the time from development of first sign or symptom to the return to normal skin)[Daily diary kept by subject during an episode. Healing time derived from this.]

Secondary Outcome Measures

Name	Time	Method
Acceptability of the application of honey as measured by a visual analogue scale[At final visit];Pain resolution (defined as the time from first experiencing pain to total resolution of pain)[Daily diary kept by subject during an episode. Outcome derived from this.];Pain severity[Daily diary kept by subject during an episode. Outcome derived from this.];Lesion severity[Daily diary kept by subject during an episode. Outcome derived from this.]