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Relationship Between Microcirculatory Flow Alterations and Tissue Metabolism

Completed
Conditions
Cardiac Surgery
Registration Number
NCT00547859
Lead Sponsor
Medical Centre Leeuwarden
Brief Summary

The purpose of this study is to correlate microcirculatory flow and rectal anaerobe cellular CO2 production in patients after cardiac surgery. The hypothesis is that such a correlation exists.

Detailed Description

Sidestream Darkfield imaging is used to determine rectal microcirculatory flow in patients after postoperative cardiac surgery. At the same time PCO2 gap is established by monitoring rectal CO2 (tonometry) and arterial CO2 After initial enrollment and first analysis we also includes a control group with equal inclusion criteria for sublingual SDF imaging.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • cardiac surgery
  • informed consent
  • age > 18
Exclusion Criteria
  • pregnancy
  • off pump procedure
  • rectal fecal contamination

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Relation between MFI (by SDF) and capno6 months
Secondary Outcome Measures
NameTimeMethod
Relevance of changes in flow and metabolism6 months

Trial Locations

Locations (1)

Department of ICU

🇳🇱

Leeuwarden, PO box 888, Netherlands

Department of ICU
🇳🇱Leeuwarden, PO box 888, Netherlands

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