Acute Effects of Standing on Glycemia in Prediabetic Adults: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Blood sugar area under the curve
研究概览
简要总结
The study is a crossover, pilot trial examining the acute effects of standing on blood sugar in prediabetic, working adults. Participants will complete oral glucose tolerance testing, once while sitting and once while standing. They will also wear a continuous blood sugar monitor once while sitting at their desk for a week and once while using their desk as a sit-stand desk with a goal of standing intermittently for at least half of the work day. Physical activity levels will be measured with an accelerometer. The primary study hypothesis is that blood sugar will differ between the sitting and standing conditions for each of the tests performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Fasting blood glucose >100 mg/dl
- •Employed full-time working at least 35 hours/week
- •Able to safely begin a light physical activity program
排除标准
- •Heart disease
- •Renal disease
- •Peripheral neuropathy
- •Retinopathy
- •Lower limb amputation
- •pregnancy
- •active substance abuse
- •current smoker
- •psychiatric disorder
- •severe visual impairment
- •immune-compromised individuals,
- •enrollment in a physical activity study
- •use of insulin or an insulin pump
结局指标
主要结局
Blood sugar area under the curve
时间窗: 2 hours
The area under the curve following the 2 hour blood sugar tests.
次要结局
- Accelerometer counts(4 hours and 2 5 day periods)