SLCTR/2014/016Not yet recruiting未知
Effect of pentoxyfylline on histological activity and fibrosis of patients with nonalcoholic steatohepatitis
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Not yet recruiting
- Enrollment
- 30
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •1. Ultrasonographic evidence of fatty liver
- •2. Nonalcoholic fatty liver disease activity score greater than or equal to 5 on liver histopathology
Exclusion Criteria
- •1. Significant alcohol intake(more than 20 gm /day)
- •2. History of taking drugs that may cause fatty liver(i.e.tamoxifen, valproic acid, amiodarone, methotrexate) or history of taking drugs that have shown benefit in previous Nonalcoholic steatohepatitis studies(i.e.vitamin E ,metformin, thiazolidinedione, fibrates)
- •3. Chronic viral hepatitis(HBV , HCV)
- •4. Pregnancy
- •5. Co-morbid conditions(Chronic Obstructive Pulmonary Disease ,Chronic Kidney Disease, Congestive CF, Myocardial infarction)
- •6. Liver failure
- •7. Hypothyroidism
- •8. Patient who fails to give consent for paired biopsy
- •9. Wilson's disease and Hemochromatosis
Investigators
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