Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High-flow Nasal Cannula Oxygen.
- Conditions
- Respiratory Failure
- Registration Number
- NCT01994928
- Lead Sponsor
- Universitätsklinikum Hamburg-Eppendorf
- Brief Summary
Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask. It seems probable that high flow nasal cannula oxygen, which is used in the treatment of patients with hypoxemic respiratory failure, is equally effective in preventing the development of hypoxemia during intubation. In this prospective randomized study preoxygenation using high flow nasal cannula oxygen is compared with preoxygenation via nose-mouth mask in patients with hypoxemic respiratory failure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- patients treated in an intensive care unit
- indication for intubation
- presence of hypoxemic (SaO2/fraction of inspired oxygen(FiO2): 300 or less) respiratory failure
- informed consent
- blocked nasopharynx
- contraindications for nose-mouth mask or high flow nasal cannula oxygen
- expected difficult airway
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Mean decrease in the saturation of oxygen (SpO2) during intubation. during intubation Mean decrease in the saturation of oxygen measured by pulse oximetry (SpO2 \[%\]) during intubation.
- Secondary Outcome Measures
Name Time Method Changes in blood gases after intubation. 30 minutes after intubation Changes in arterial blood gases collected from arterial line (PaO2/FiO2 \[mmHg\] and PaCO2 \[mmHg\]) after intubation.
Trial Locations
- Locations (1)
Universitätsklinikum Hamburg-Eppendorf, Department of Intensive Care Medicine
🇩🇪Hamburg, Germany
Universitätsklinikum Hamburg-Eppendorf, Department of Intensive Care Medicine🇩🇪Hamburg, Germany