Prospective Randomised Study on Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High Flow Nasal Cannula Oxygen.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Respiratory Failure
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Mean decrease in the saturation of oxygen (SpO2) during intubation.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask. It seems probable that high flow nasal cannula oxygen, which is used in the treatment of patients with hypoxemic respiratory failure, is equally effective in preventing the development of hypoxemia during intubation. In this prospective randomized study preoxygenation using high flow nasal cannula oxygen is compared with preoxygenation via nose-mouth mask in patients with hypoxemic respiratory failure.
Investigators
Stefan Kluge
Prof. Dr. Stefan Kluge
Universitätsklinikum Hamburg-Eppendorf
Eligibility Criteria
Inclusion Criteria
- •patients treated in an intensive care unit
- •indication for intubation
- •presence of hypoxemic (SaO2/fraction of inspired oxygen(FiO2): 300 or less) respiratory failure
- •informed consent
Exclusion Criteria
- •blocked nasopharynx
- •contraindications for nose-mouth mask or high flow nasal cannula oxygen
- •expected difficult airway
Outcomes
Primary Outcomes
Mean decrease in the saturation of oxygen (SpO2) during intubation.
Time Frame: during intubation
Mean decrease in the saturation of oxygen measured by pulse oximetry (SpO2 \[%\]) during intubation.
Secondary Outcomes
- Changes in blood gases after intubation.(30 minutes after intubation)