Prospective Randomised Study on Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High Flow Nasal Cannula Oxygen.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Mean decrease in the saturation of oxygen (SpO2) during intubation.
研究概览
简要总结
Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask. It seems probable that high flow nasal cannula oxygen, which is used in the treatment of patients with hypoxemic respiratory failure, is equally effective in preventing the development of hypoxemia during intubation. In this prospective randomized study preoxygenation using high flow nasal cannula oxygen is compared with preoxygenation via nose-mouth mask in patients with hypoxemic respiratory failure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients treated in an intensive care unit
- •indication for intubation
- •presence of hypoxemic (SaO2/fraction of inspired oxygen(FiO2): 300 or less) respiratory failure
- •informed consent
排除标准
- •blocked nasopharynx
- •contraindications for nose-mouth mask or high flow nasal cannula oxygen
- •expected difficult airway
结局指标
主要结局
Mean decrease in the saturation of oxygen (SpO2) during intubation.
时间窗: during intubation
Mean decrease in the saturation of oxygen measured by pulse oximetry (SpO2 \[%\]) during intubation.
次要结局
- Changes in blood gases after intubation.(30 minutes after intubation)
研究者
Stefan Kluge
Prof. Dr. Stefan Kluge
Universitätsklinikum Hamburg-Eppendorf