Blood concentration of undercarboxylated osteocalcin (uc - OC) in hemodialysis patients using warfari
Not Applicable
- Conditions
- Chronic renal failure
- Registration Number
- JPRN-UMIN000034633
- Lead Sponsor
- Saitama Tsukinomori Clinic
- Brief Summary
The median OC of WF-HD was 106.1 ng / mL and the median uc-OC was 49.5 ng / mL, which were higher than the median OC of 14.2 ng / mL and the median uc-OC of 2.0 ng / mL in HS (P <0.001). The median OC / uc-OC ratio was 0.63 for WF-HD, which was higher than the median 0.22 for non WF-HD and 0.16 for HS (P <0.001). Vitamin K1 was lower in WF-HD and non WF-HD than in HS (P <0.001). Vitamin K2 was not significantly different in the three groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
Patients complicated with serious diseases such as cancer, hematological disorders, and liver cirrhosis
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in blood concentration of uc - OC, bone alkaline phosphatase (BAP), tartarate - resistant acid phosphatase - 5 b (TRACP - 5 b) in hemodialysis patients taking warfarin and those not taking
- Secondary Outcome Measures
Name Time Method