MedPath

Early Systolic Notching in Pulmonary Embolism

Completed
Conditions
Pulmonary Embolism
Registration Number
NCT04413825
Lead Sponsor
Gazi University
Brief Summary

Venous thromboembolism (VTE), clinically seen as deep vein thrombosis (DVT) or pulmonary embolism (PE), is the third most common acute cardiovascular syndrome after myocardial infarction and stroke. In a study conducted by critical care and emergency physicians, lung ultrasonography (US) for pleural infarction areas, lower extremity venous US in terms of DVT, and focused cardiac US in terms of right ventricular strain were demonstrated with different diagnostic values for PE. However, no ultrasonographic method alone has a high diagnostic value for PE alone in the literature. In a recent study, it is stated that a new cardiac finding (early systolic notch- ESN) has high sensitivity (92%) and specificity (99%) in massive and submassive emboli. However, the limited patient population and the exclusion of many patient groups limits the applicability of the study and its use in other patient groups. With this study, it was aimed to determine the diagnostic value of ESN finding within the emergency department conditions by keeping the patient population wider.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
180
Inclusion Criteria
  • Patients undergoing pulmonary CT angiography with suspicion of pulmonary embolism
Exclusion Criteria
  • Pregnant women,
  • Patients under 18 years of age,
  • Those who received thrombolytic therapy,
  • Poor ultrasound imaging.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To determine the diagnostic accuracy of the ESN finding6 months

What is the diagnostic value of ESN finding in patients with PE diagnosed with pulmonary CT angio?

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Gazi University Facaulty of Medicine

🇹🇷

Ankara, Turkey

© Copyright 2025. All Rights Reserved by MedPath