跳至主要内容
临床试验/NCT04413825
NCT04413825已完成不适用

Diagnostic Accuracy of Early Systolic Notching in Pulmonary Embolism

Gazi University1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2020年6月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
180
试验地点
1
主要终点
To determine the diagnostic accuracy of the ESN finding

研究概览

简要总结

Venous thromboembolism (VTE), clinically seen as deep vein thrombosis (DVT) or pulmonary embolism (PE), is the third most common acute cardiovascular syndrome after myocardial infarction and stroke. In a study conducted by critical care and emergency physicians, lung ultrasonography (US) for pleural infarction areas, lower extremity venous US in terms of DVT, and focused cardiac US in terms of right ventricular strain were demonstrated with different diagnostic values for PE. However, no ultrasonographic method alone has a high diagnostic value for PE alone in the literature. In a recent study, it is stated that a new cardiac finding (early systolic notch- ESN) has high sensitivity (92%) and specificity (99%) in massive and submassive emboli. However, the limited patient population and the exclusion of many patient groups limits the applicability of the study and its use in other patient groups. With this study, it was aimed to determine the diagnostic value of ESN finding within the emergency department conditions by keeping the patient population wider.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients undergoing pulmonary CT angiography with suspicion of pulmonary embolism

排除标准

  • Pregnant women,
  • Patients under 18 years of age,
  • Those who received thrombolytic therapy,
  • Poor ultrasound imaging.

结局指标

主要结局

To determine the diagnostic accuracy of the ESN finding

时间窗: 6 months

What is the diagnostic value of ESN finding in patients with PE diagnosed with pulmonary CT angio?

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mehmet Ali Aslaner

Assos. Prof.

Gazi University

研究点 (1)

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