Prognosis and quality of life in patients with aphasia: a prospective follow-up study.
Recruiting
- Conditions
- Aphasialanguage disorder10007963
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
Stroke patients with aphasia < six days post onset; Age 18 years or more; Language near native; Testable with the ScreeLing within six days post onset.
Exclusion Criteria
Prior stroke and/or aphasia; (suspected) Dementia; Severe dysartria and/ or verbal apraxia; Developmental dyslexia; Severe perceptual, visual and/or hearing deficit; Stroke due to a subarachnoidal hemorrhage; Illiteracy; Recurrent stroke; Recent psychiatric history.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p> A. Prognosis<br /><br>The primary outcome measure is the severity of the linguistic deficits at<br /><br>several time points in the first year post-stroke, measured with the ScreeLing,<br /><br>a test that measures functioning on three linguistic levels: semantics,<br /><br>phonology and syntax.<br /><br><br /><br><br /><br>B. Quality of Life<br /><br>The primary outcome measure concern the quality of life as measured with the<br /><br>Health Utilities Index at several time points in the first year post-stroke. </p><br>
- Secondary Outcome Measures
Name Time Method <p> A. Prognosis<br /><br>The secondary outcome measures are the severity of aphasia measured with the<br /><br>Token Test and the verbal communication measured with the Aphasia Severity<br /><br>Rating Scale, at several time points in the first year post-stroke. In<br /><br>addition, the extent of the recovery of aphasia and the performance in the<br /><br>non-linguistic cognitive domains at 3 months and at one year post onset.<br /><br><br /><br>B. Quality of life<br /><br>The secondary outcome measures are the EuroQol, the modified Rankin Scale and<br /><br>the Barthel Index, which are respectively related to the quality of life and<br /><br>daily life functioning, measured at several time points in the first year<br /><br>post-stroke. </p><br>