Comparison Of Ultrasound Guided Transversus Abdominis Plane Block (TAP) and Local Infiltration Analgesia During Laparoscopic Cholecystectomy Surgery
Overview
- Phase
- Phase 4
- Intervention
- Levobupivacaine 0.5%
- Conditions
- Cholecystectomy, Laparoscopic
- Sponsor
- Duzce University
- Enrollment
- 75
- Locations
- 1
- Primary Endpoint
- postoperative pain scores
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Postoperative pain is a significant cause of increased morbidity in the perioperative period, leading to patient discomfort and greater hospital length of stay. Laparoscopic cholecystectomy associated with significant postoperative pain, a substantial component of which is derived from abdominal wall incisions. Ultrasound-guided TAP block increasingly has been used for providing pain relief following abdominal surgery. We designed this study with the hypothesis that, administering TAP block with levobupivacaine in laparoscopic cholecystectomy provides superior analgesic effects than port-side infiltration.
Detailed Description
In this randomized and double-blind study, 75 patients, American Society of Anesthesiology (ASA) I-II risk group, between the ages of 20-60, who will undergo elective laporoscopic cholecystectomy operation under general anesthesia will be accepted. The patients will be divided into three groups and they will be given postoperative pain treatment with patient-controlled analgesia device. In hours of postoperative 1, 2, 4, 8, 12, 16 and 24, Visual analog scale (VAS) I (superficial pain), VAS II (deep pain), postoperative total analgesic proportion, nausea and vomiting, evaluation postoperative sedation score will be recorded (as conscious:0, asleep:1, deep sleep:2 ) in hours of postoperative 1, 2, 4, 8, 12, 16 and 24.
Investigators
gulbin sezen
assistant of professor
Duzce University
Eligibility Criteria
Inclusion Criteria
- •ASA I-II risk group,
- •between the ages of 20-60,
- •undergo elective laporoscopic cholecystectomy operation under general anesthesia
Exclusion Criteria
- •allergy to anesthetic medication,
- •coronary artery patients,
- •obese patients,
- •emergencies,
- •pregnants,
- •abdomen operation history
- •heart block
Arms & Interventions
local infiltration
Group L (n=25) will be given total 30 ml 0.25 % levobupivacaine infiltration around trocar-site with injector in sterilized conditions without administering TAP block at the end of the operation
Intervention: Levobupivacaine 0.5%
TAP
Group T (n=25) will be given bilateral total 30 ml 0.25 % levobupivacaine administering TAP block under the guidance of ultrasound at the preoperative period.
Intervention: Levobupivacaine 0.25 %
Outcomes
Primary Outcomes
postoperative pain scores
Time Frame: 24 hours
VAS I (superficial pain), VAS II (deep pain) recorded in hours of postoperative 1, 2, 4, 8, 12, 16 and 24 h,
Secondary Outcomes
- postoperative total analgesic consumption(Postoperatively 24 h)