Evaluation of Different Continuous Positive Airway Pressure (CPAP) Systems in Patients With Acute Respiratory Failure
Completed
- Conditions
- Acute Respiratory Failure
- Registration Number
- NCT00876473
- Lead Sponsor
- Policlinico Hospital
- Brief Summary
The aim of this study is to evaluate the performance, the tolerability and the efficacy on gas-exchange of different CPAP (Continuous Positive Airway Pressure) systems.
- Detailed Description
Three CPAP systems are studied for each patient at the same level of PEEP: 1) continuous high-flow CPAP with fixed value PEEP valve; 2) continuous high-flow CPAP with Boussignac PEEP valve; 3) demand flow CPAP, supplied by a ventilator.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Intubated-tracheostomized subjects receiving CPAP during the weaning from invasive mechanical ventilation
Exclusion Criteria
- Hemodynamic instability
- Barotrauma
- Severe myopathy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Respiratory mechanics, work of breathing, end-expiratory lung volume (EELV) and gas exchange 30 minutes
- Secondary Outcome Measures
Name Time Method Comfort of breathing 30 minutes
Trial Locations
- Locations (1)
Policlinico Hospital
🇮🇹Milan, Italy
Policlinico Hospital🇮🇹Milan, Italy