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临床试验/NCT00876473
NCT00876473已完成不适用

The CPAP in Patients Affected by Acute Respiratory Failure

Policlinico Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2009年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
Respiratory mechanics, work of breathing, end-expiratory lung volume (EELV) and gas exchange

研究概览

简要总结

The aim of this study is to evaluate the performance, the tolerability and the efficacy on gas-exchange of different CPAP (Continuous Positive Airway Pressure) systems.

详细描述

Three CPAP systems are studied for each patient at the same level of PEEP: 1) continuous high-flow CPAP with fixed value PEEP valve; 2) continuous high-flow CPAP with Boussignac PEEP valve; 3) demand flow CPAP, supplied by a ventilator.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Intubated-tracheostomized subjects receiving CPAP during the weaning from invasive mechanical ventilation

排除标准

  • Hemodynamic instability
  • Barotrauma
  • Severe myopathy

结局指标

主要结局

Respiratory mechanics, work of breathing, end-expiratory lung volume (EELV) and gas exchange

时间窗: 30 minutes

次要结局

  • Comfort of breathing(30 minutes)

研究者

发起方
Policlinico Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Davide Chiumello

MD

Policlinico Hospital

研究点 (1)

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