Pre-emptive Ultrasound Guided Superior Hypogastric Plexus Block in Pelvic Cancer Surgeries : a Randomized Double-Blinded Study
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- morphine consumption
Study Overview
Brief Summary
The superior hypogastric plexus (SHP) is a retroperitoneal structure with a predominance of afferent sympathetic nerve fibers. The perception of central pelvic pain is thought mainly to involve transmission through this plexus. Therefore, blocking or of SHP has been used to treat pelvic pain.
Detailed Description
Ultrasound guided superior hypogastric plexus block there is 2 equal groups:
Group S (SHPB group 18 patients) ultrasound guided SHPB is done after induction of balanced general anesthesia (fentanyl, propofol and rocuronium) using 20 ml Bupivacaine 0.5% before skin incision, Group C (Control group 18 patients) in which same technique will be done but using normal saline 0.9% instead of bupivacaine. Patients of both groups will receive patient controlled analgesia using morphine with continous background infusion of morphine 1.5 mg/h with adding granisterone 2mg/60 ml and ability to give bolus of 0.5 mg morphine on demand.
• Dosing and administration; Group S (SHPB group 18 ultrasound guided SHPB ) using 20 ml Bupivacaine 0.5% before skin incision.
Group C (Control group 18 patients) in which same technique will be done but using normal saline 0.9%
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Masking Description
Randomization is done using computer generated sequence. Concealment will be achieved by opaque envelope.
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •ASA II,III.
- •Patients undergoing pelvic surgeries.
Exclusion Criteria
- •Patients refusal,
- •Coagulopathy,
- •Infection.
Outcomes
Primary Outcomes
morphine consumption
Time Frame: baseline till 24 hours postoperative
Total 24 hours morphine consumption in milligrams
Secondary Outcomes
- Visual analogue scale (VAS)(Visual analogue scale (VAS) at baseline till 24 hours postoperative)
Investigators
Mohammed Abdelfattah Abdelwadod
Mohammed Abdelfattah Abdelwadod
National Cancer Institute, Egypt