Postoperative pain relief in Total Knee Arthroplasty: Ultrasound-guided Adductor Canal Block vs Local Intraarticular Infiltration, A Randomised, Prospective, Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To estimate the total morphine consumption in the three groups
研究概览
简要总结
In conclusion, in patients undergoing elective unilateral total knee arthroplasty(TKA), adductor canal block(ACB) was found to be superior to both local intraarticular infiltration and control group in reducing the 24 hour morphine consumption, lowering VAS scores at rest and with movement, prolonging time to first analgesia, reducing requirement of rescue analgesia, lowering worst VAS score during timed up and go test(TUG test) and showing better patient satisfaction scores. The incidence of opioid-related side-effects was comparable among the three groups. Adductor canal block also was not associated with any complications related to its technique, hence ACB can be considered a safe technique to be used in patients undergoing unilateral TKA for postoperative analgesia. While local intra-articular infiltration was found to be superior to control group in reducing 24 hour PCA morphine consumption, lowering VAS scores both at rest and with movement, prolonging time to first analgesia, reducing the requirement of rescue analgesia and showing better patient satisfaction compared to control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA physical status I-III scheduled for elective primary unilateral knee arthroplasty.
排除标准
- •1.Age > 80 years 2.ASA IV / V 3.Bilateral / Revision TKA 4.Morbid obesity (BMI ≥ 40 ) 5.History of focal neurological deficit 6.History of sensory or motor disorders of limb to be operated 7.History of allergy to local anaesthetics , clonidine 8.History of regular opioid use 9.Local site infection 10.Patient refusal to partake in the study.
- •11.Contraindication to spinal anaesthesia.
结局指标
主要结局
To estimate the total morphine consumption in the three groups
时间窗: 24 hours postopertively
次要结局
- To assess pain scores at rest and movement using visual analogue scale(0,4,8,12,24 hours postoperatively)
- To estimate the time to first use of patient controlled analgesia device(24 hours postoperatively)
- To compare the side effects associated with morphine consumption in the three groups(24 hours postoperatively)
- To estimate the worst pain during and time taken to perform the timed get up and go (TUG) test(24 hours postoperatively)
- To assess patient satisfaction(24 hours postoperatively)