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Clinical Trials/NCT03958942
NCT03958942
Unknown
Not Applicable

Effect of Bilateral Ultrasound Guided Quadratus Lumborum Block Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response Following Major Lower Abdominal Cancer Surgery

Assiut University1 site in 1 country60 target enrollmentJune 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Assiut University
Enrollment
60
Locations
1
Primary Endpoint
postoperative pain
Last Updated
6 years ago

Overview

Brief Summary

This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.

Registry
clinicaltrials.gov
Start Date
June 1, 2019
End Date
March 1, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmad Mohammad Abd El-Rahman

assisstant professor of Anesthesia, ICU, and Pain Management

Assiut University

Eligibility Criteria

Inclusion Criteria

  • ASA II, III
  • Weight 50 - 85 kg.
  • Scheduled for major lower abdominal cancer surgery (radical cystectomy, total abdominal hysterectomy).

Exclusion Criteria

  • Patients with a history of relevant drug allergy.
  • Coagulation disorders.
  • Opioid dependence.
  • Local infection at the vicinity of the block site.
  • Patients with psychiatric illnesses that would interfere with perception and assessment of pain

Outcomes

Primary Outcomes

postoperative pain

Time Frame: first 24 hours postoperatively

postoperative pain intensity.

Secondary Outcomes

  • side effects(first 24 hours postoperatively)
  • postoperative inflammatory response(first 24 hours postoperatively)

Study Sites (1)

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