Electroacupuncture for Painful Chemotherapy-induced Peripheral Neuropathy: A Multicenter Randomized Controlled Clinical Trial

Korea Institute of Oriental Medicine0 个研究点目标入组 146 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

暂无简介。

•1. Males and females aged 20 years and older
•2. Patients who had received neurotoxic chemotherapy with a diagnosis of cancer
•3. Symptoms of painful peripheral neuropathy of duration (= 1 month and =5 years) attributed to chemotherapy with taxane or platinum agents, and a score = 4 out of 10 on the NRS scale.
•4. No use of medications to prevent or treat neuropathy within 2 weeks before screening.
•5. ECOG PS of 0-2
•6. Life expectancy = 6 months
•7. Agreed with written informed consent

•1. Pre-existing or history of peripheral neuropathy due to any cause other than chemotherapy (diabetes, peripheral vascular disease, HIV, alcohol, toxin, hereditary, nerve compression injuries, etc.)
•2.Known hypersensitivity reaction after acupuncture treatment or inability to cooperate with acupuncture procedure
•3. A subject with history of allergies to study drug (gabapentin) or with rare hereditary problems of galactose intolerance, or glucose-galactose malabsorption
•4. Received acupuncture, moxibustion, cupping or herbal medicine for peripheral neuropathy last 4 weeks
•5. Cardiovascular disorder (e.g. arrhythmia) or using pacemaker
•6. BUN, creatinine > 1.5 UNL
•7. Pregnant, expecting pregnant or nursing women
•8. Those who are not willing to comply with this study protocol

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