Administration of Vaginal and Rectal Progesterone During FET Cycles

Completed

• Conditions: Infertility

• Registration Number: NCT03470610
• Lead Sponsor: Thor Haahr

Brief Summary

Observational study of reproductive outcome after frozen embryo transfer in HRT with vaginal and rectal progesterone.

Detailed Description

Cohort of patients treated with autologous blastocyst at the Fertility clinic Skive Regional Hospital in HRT cycle. Estradiol stimulation started on second cycle day and on day 12 - 20 vaginal and rectal progesterone is added. Blastocyst transfer on 6th progesterone treatment day. Serum progesterone and hCG measurement 9 or 11 days after embryo transfer.

Study Timeline

• Study Start: 2018-02-01
• Study First Submitted: 2018-03-12
• Study First Submitted QC: 2018-03-18
• Study First Posted: 2018-03-20
• Primary Completion: 2019-02-01
• Status Verified: 2019-09
• Study Completion: 2019-09-01
• Last Update Submitted: 2019-09-09
• Last Update Posted: 2019-09-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 277

Inclusion Criteria

• Frozen embryo transfer cycles in HRT cycles

Exclusion Criteria

• Donor frozen embryo transfer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ongoing pregnancy	4 month	gestational week 12

Secondary Outcome Measures

Name	Time	Method
Pregnancy loss	4 month	pregnancy loss before week 7
pregnancy rate	4 month	positive hCG

Trial Locations

Locations (1)

Fertility Clinic Regional Hospital Skive; 🇩🇰 Skive, Denmark