Intensive Versus Standard Hemodialysis CVC Dysfunction Protocol

Not Applicable

Completed

• Conditions: Chronic Renal Insufficiency

• Registration Number: NCT02474810
• Lead Sponsor: Nova Scotia Health Authority

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-6-16
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> - All adults undergoing HD with a tunneled CVC (both newly inserted CVCs as well as<br> pre-existing CVCs) will be included.<br><br>Exclusion Criteria:<br><br> - Patients were excluded from using the CVC dysfunction protocols if they had a known<br> allergy or intolerance to rt-PA.<br><br> - A physician order to proceed with the CVC dysfunction protocols was required if they<br> met one of the following criteria:<br><br> - CVC line insertion or exchange within 72 hours;<br><br> - any surgery, organ biopsy, obstetrical delivery within 72 hours;<br><br> - active bleeding; bleeding disorders; hemoglobin decrease greater than 20 g/L over 2<br> weeks;<br><br> - active pericarditis; arterial puncture within 48 hours;<br><br> - bacteremia with positive blood cultures.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Alteplase use

Secondary Outcome Measures

Name	Time	Method
Rate of bacteremia;Cost of alteplase