Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Change in movement time
研究概览
简要总结
This study examines the effect of non-invasive brain stimulation targeting different brain areas on movement of the affected arm post-stroke. Participants will receive stimulation to each of 3 different brain areas combined with a session of arm exercise.
详细描述
Small improvements in affected arm movement can be made with intensive physical practice. These improvements could potentially be enhanced by combining non-invasive brain stimulation with practice.
To develop such an intervention, it is necessary to understand which brain areas should be stimulated in which types of patients. It is probably more beneficial to target one side of the brain vs. the other, for example, depending on the characteristics of the stroke.
This study will examine the effect of stimulating one side of the brain vs. the other on the amount of improvement that occurs from physically practicing functional arm movements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The individual that conducts the tests of arm movement will be unaware of which brain area was stimulated.
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •More than 6 months post-stroke
- •Loss of voluntary finger movement in the affected hand
- •Some voluntary movement of affected shoulder and/or elbow
排除标准
- •Brainstem or cerebellar stroke
- •Severe cognitive or language deficits
- •Epilepsy or other seizure disorder
- •Central nervous system disease or disorder other than stroke
结局指标
主要结局
Change in movement time
时间窗: Baseline and 1 Day
Percentage change in time it takes to move the arm a standardized distance
次要结局
- Change in maximum reaching distance(Baseline and 1 Day)
- Change in hand path kinematics(Baseline and 1 Day)