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Clinical Trials/NCT04215263
NCT04215263
Completed
Not Applicable

Risk Factors of Post Operative Cognitive Dysfunction (POCD) in General Anesthesia Patients Underwent Noncardiac and Non Neurological Procedures.

Indonesia University1 site in 1 country109 target enrollmentMay 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Undergoing General Anaesthesia
Sponsor
Indonesia University
Enrollment
109
Locations
1
Primary Endpoint
Mini International Neuropsychiatric Interview
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The study was a prospective cohort study to assess the effect of age, duration of anesthesia, repeated surgery, and type of surgery on cognitive impairment in 108 geriatric patients (≥60 years) who underwent general anesthesia for non-neurologic noncardiac surgery.

Detailed Description

The study was a prospective cohort study, assessing the effect of age, duration of anesthesia, repeated surgery, and type of surgery on cognitive impairment in 108 geriatric patients (≥60 years) who underwent general anesthesia for non-neurologic noncardiac surgery. The study used cognitive tests such as RAVLT, TMT, and Digit span tests. POCD definition is reduction in postoperative cognitive function by as much as 20% at a minimum of 2 cognitive tests.

Registry
clinicaltrials.gov
Start Date
May 1, 2019
End Date
July 5, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Aries Perdana

Principal Investigator

Indonesia University

Eligibility Criteria

Inclusion Criteria

  • geriatric patient (age over 60) underwent noncardiac non-neurological procedure under general anesthesia
  • patient can do reading and writing
  • patient can speak in Bahasa
  • signing informed consent

Exclusion Criteria

  • patient with cognitive impairment or psychiatric disorder such as delirium, amnesia, anxiety disorder, or depression.
  • patient under psychotropic drugs or narcotics.
  • patient with history of brain tumor, head injury or motoric disturbance and disability that can disturbed neurocognitive test

Outcomes

Primary Outcomes

Mini International Neuropsychiatric Interview

Time Frame: 7 days

Score was assessed using 6 forms

Study Sites (1)

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