Efficacy of DE-MRI-guided fibrosis ablation vs. conventional catheter ablation of atrial fibrillatio

Not Applicable

Completed

• Conditions: Atrial fibrillation (AF); Circulatory System; Atrial fibrillation and flutter

• Registration Number: ISRCTN17213748
• Lead Sponsor: St Jude Medical

Brief Summary

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33600025/ (added 13/01/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-12-08
• Study Completion: 2019-04-01
• Last Update Posted: 24 January 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 900

Inclusion Criteria

1. Patients with persistent AF defined as 7 days or more of AF as evidenced by either:
1.1 rhythm strip or
1.2. written documentation
2. Undergoing first AF ablation as per recent HRS consensus document (has not had a previous left atrial ablation or cardiac surgical procedure)
3. Age = 18 years

Exclusion Criteria

1. Contraindication for DE-MRI with a full dose of contrast agent
2. Contraindication to beta blockers, if necessary, for DE-MRI
3. Women currently pregnant
4. Mental or physical inability to take part in the study
5. Inability to be placed in MRI due to body mass or body habitus
6. Known terminally ill patients
7. Subjects without daily access to a smart phone or tablet compatible with the ECG Check application and ability to upload ECG tracings for the entire follow up period.

Study & Design

• Study Type: Interventional
• Study Design: Not specified