Laser Acupuncture in Egyptian Systemic Lupus Females With Insulin Resistance
- Conditions
- Systemic Lupus ErythematosusPreDiabetes
- Interventions
- Device: sham laserDevice: active laser
- Registration Number
- NCT05632029
- Lead Sponsor
- Cairo University
- Brief Summary
glucose hemosatasis, oxidative stress, abnormalities of blood pressures, and high inflammatory status is high presented in lupus patients.
- Detailed Description
64 lupus prediabetic women will equally distributed to group A (n =32 that will receive laser acupuncture (active) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont) or group B (n =32 this group will receive the same protocol of group A but the points will be sham points)
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 64
- prediabetic lupus females (n =64)
- obesity diabetes heart or respiratory problems
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description laser (sham laser) sham laser 32 lupus prediabetic women will receive laser acupuncture (sham . i.e power of the device will be zero) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont) laser (active laser) active laser 32 lupus prediabetic women will receive laser acupuncture (active laser) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont)
- Primary Outcome Measures
Name Time Method Malondialdehyde It will be measured after 4 weeks of laser application oxidative stress indicator
- Secondary Outcome Measures
Name Time Method erythrocyte sedimentation rate (at first hour) It will be measured after 4 weeks of laser application it will be measured in serum
erythrocyte sedimentation rate (at second hour) It will be measured after 4 weeks of laser application it will be measured in serum
adenosine triphosphate It will be measured after 4 weeks of laser application it a measure for energy production
Nitrate It will be measured after 4 weeks of laser application it will be measured in serum
diastolic blood pressure It will be measured after 4 weeks of laser application manual sphygmomanometer
blood glucose It will be measured after 4 weeks of laser application it will be measured in fasting status
Glutathione It will be measured after 4 weeks of laser application it will be measured in serum
C reactive protein It will be measured after 4 weeks of laser application it will be measured in serum
systolic blood pressure It will be measured after 4 weeks of laser application manual sphygmomanometer
Trial Locations
- Locations (1)
Cairo Unoversity
🇪🇬Giza, Egypt