Is There Intravascular Hemolysis in Patients With Pulmonary Hypertension?
- Conditions
- Pulmonary Artery Hypertension
- Registration Number
- NCT00502398
- Lead Sponsor
- Rabin Medical Center
- Brief Summary
Patients with hemolytic disorders (e.g. sickle cell anemia or thalassemia) are known to develop pulmonary hypertension. Hemolysis is where red blood cells are destroyed and their contents released into the circulation. It is thought that these red-cell contents cause constriction and thrombosis of the blood vessels in the lungs. Conversely, it is possible that patients with pulmonary hypertension have hemolysis.
In this study we will be drawing blood from a range of patients and normal controls for a panel of blood tests related to hemolysis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
One of the following four conditions :
- Pulmonary artery hypertension
- Obstructive sleep apnea with pulmonary hypertension
- Lung transplant candidates without pulmonary hypertension
- Normal Controls
Exclusion Criteria
- Known hemolytic disorder
- Recent blood loss (<3 months)
- Recent blood transfusion (<3 months)
- Liver disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Pulmonary Institute, Rabin Medical Center (Beilinson campus)
🇮🇱Petach Tikva, Israel