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Effects of testosterone treatment on endothelial function among transgender male

Recruiting
Conditions
Adult healthy transgender men
Endothelial function
Flow mediated dilatation
Testosterone
Transgender men
Registration Number
TCTR20240709003
Lead Sponsor
Ratchadapisek Research Funds
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
10
Inclusion Criteria

Women age 20-40 years who desire to be transgender male
have not received GAHT and performed gender reassignment surgery

Exclusion Criteria

Having history of clinical atherosclerosis, metabolic disease, hypertension, gynecologic disease
Smoking
Using cardiovascular medication or medication that would affect
vasoconstriction or vasodilation or testosterone metabolism

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
flow mediated dilatation (FMD) day 0 and 3 months brachial artery ultrasound
Secondary Outcome Measures
NameTimeMethod
Comparison of lipid profile and Hb/Hct between pre and posttreatment with supraphysiologic testosterone therapy among transgender male day 0 and 3 months blood test
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