Oxygen with exercise in idiopathic interstitial pneumonia

Not Applicable

Completed

• Conditions: Idiopathic interstitial pneumonia; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12611001285943
• Lead Sponsor: Royal Prince Alfred Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-12-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

Patients 18 - 80 yrs.
Patients able to perform exercise test as determined following clinical assessment.
Patients who desaturate to < 88% during a 6 minute walk test (6MWT)
Patients able to give informed consent.
Patients with idiopathic interstitial pneumonia (IIP), according to American Thoracic Society /European Respiratory Society criteria.
Absence of daytime resting hypoxaemia (ie with PaO2 > 55mmHg).

Exclusion Criteria

Patients not able to give informed consent.
Patients considered unable to complete exercise test by their physician.
Presence of daytime resting hypoxaemia (PaO2 less than or equal to 55mmHg).
Presence of hypercapnia (PaCO2 > 45mmHg) at baseline
Patients with absolute contraindications to exercise testing including:

Aortic aneursym
Current viral illness
Unstable angina/acute ECG changes of ischaemia.
Myocardial infarction within the last 4 weeks.
Severe hypertension (systolic >240 mmHg; diastolic >120 mmHg).
Poorly controlled heart failure.
Myocarditis.
Exacerbation of asthma.
Severe aortic stenosis.
Acute pulmonary embolus / thrombus / venous thromboembolic disorders.
Pulmonary oedema.
Mental Impairment

Study & Design

• Study Type: Interventional
• Study Design: Not specified