The COLDICE Trial: Cryobiopsy versus Open Lung biopsy in the Diagnosis of Interstitial lung disease allianCE
Not Applicable
Completed
- Conditions
- Interstitial Lung DiseaseRespiratory - Other respiratory disorders / diseases
- Registration Number
- ACTRN12615000718549
- Lead Sponsor
- auren Troy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
Patients assessed as requiring histopathology for the diagnosis of their ILD (at specialist multidisciplinary team meetings), and considered suitable for VATS lung biopsy.
Exclusion Criteria
* Age > 80
* Resting oxyhaemoglobin saturation under 90%
* Platelets less than 100
* INR > 1.5
* Advanced comorbidities (including poorly controlled systemic hypertension, congestive cardiac failure, unstable angina, significant stroke).
* History of of adverse reaction to general anaesthesia
* Inability to provide informed consent
* Systolic pulmonary artery pressure over 40mmHg on echocardiogram or evidence of right ventricular dysfunction
* Inability to withhold anti-platelet therapy (eg aspirin or clopidogrel)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method