Clinical Application of Personal Designed 3D Printing Implants in Bone Defect Restoration
Not Applicable
- Conditions
- Defect; Internal Prosthetic Device, Implants and Grafts, Orthopedic, Bone Graft
- Interventions
- Procedure: autogenous bone graftingProcedure: 3D printing implant
- Registration Number
- NCT03166917
- Lead Sponsor
- fang guofang
- Brief Summary
Objective: Clinical application of 3D printing implant in bone defect treatment.
Study design: multicenter randomized controlled study . Methods:patients randomly grouped according to register number into internal fixation and bone graft group and 3D printing group. Reconstruct 3D models ,evaluate models preoperatively , simulate surgery in computer,design 3D implant, and 3D print implants,perform surgery with 3D implants to achieve the greatest degree of physiological reconstruction.Evaluate surgical efficacy .
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- Open fracture with bone defect
- Burst fracture of spine with bone defect
- Bone tumor with bone defect
- Bone tuberculosis with bone defect
- Nonunion with bone defect
Exclusion Criteria
- Patients who can not tolerate anesthesia and surgery due to severe impairment of heart and lung function
- Systemic or local infection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Autogenous bone grafting autogenous bone grafting autogenous bone grafting in bone defect 3D printing implant 3D printing implant 3D printing implant in bone defect
- Primary Outcome Measures
Name Time Method operative time 3 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
Zhujing hospital of southern medical university
🇨🇳Guanzhou, China
Nanfang Hospital of Southern Medical University
🇨🇳Guangzhou, China
Shenzhen Hospital of Southern Medical University
🇨🇳Shenzhen, China