Determining and comparing the effect of Adaptive Support Ventilation and Synchronized Intermittent Mandatory Ventilation on respiratory support outcomes after Coronary Artery Bypass Graft surgery, Isfahan University of Medical sciences, Chamran hospital, 2014

Vice chancellor for research, Isfahan university of medical sciences0 个研究点目标入组 64 人开始时间: 待定最近更新: 2018年2月22日

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•Main inclusion criteria: Using one of the ventilation modes (Adaptive support ventilation (ASV) or synchronized intermittent mandatory ventilation (SIMV)) on Raphael ventilator was allowed by anesthesiologist; The range of age was between 25 and 65 years; Patients did not have a history of lung diseases (Asthma, ...) or lung and heart surgeries; Patients did not have renal failure (serum creatinine more than 2), liver disease, and history of seizure and CVA; left ventricular ejection fraction was more than 30 percent; In the time of ICU entrance patients were haemodynamically stable ( respiratory rate less than 35 per minute, heart rate less than 150 per minute, mean atrial pressure less than 70 mmHg) and intra aortic balloon pump was not used.
•Main exclusion criteria: occurring unstable haemodynamic status during research (respiratory rate more than 35 per minute, heart rate more than 150 per minute, mean atrial pressure more than 70 mmHg); life threatening arrhythmia durin research like ventricular tachycardia; need to excess dosages of inotropes and vasoconstrictors during research (Dopamin more than 20 milligram per hour, norepinephrin more than 0.5 milligram per hour, dobotamin more than 25 milligram per hour, and epinephrin with any doses); Unusual bleeding after operation (chest tube drainage more than 500 ml per hour, more than 350 ml per hour for 2 hours, or more than 1000 ml at all) ; Need to anesthesia and operation again.

发起方

Vice chancellor for research, Isfahan university of medical sciences